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2001-2005

ESCODD

Establishing the background level of base oxidation in human lymphocyte DNA: results of an interlaboratory validation study.

The FASEB Journal (2005), 19, 82-84.


Schwerdtle T, Walter I, Hartwig A

Arsenic in drinking water: Exposure data, metabolism in humans and toxicological consequences.

In: Proceedings Vol 2 Euro Food Chem XIII: Macromolecules and their degradation products in food – physiological, analytical and technological aspects (2005), pp 640-643.


Hamann I, Schwerdtle T, Jahnke G, Blessing H, Hall C, Hartwig A

Copper and selenium: essential trace elements with toxicological impact.

In: Proceedings Vol 2 Euro Food Chem XIII: Macromolecules and their degradation products in food – physiological, analytical and technological aspects (2005), pp 644-647.


Berner Z, Menzel C, Zeller A, Eckhardt JD, Stüben D and Hartwig A

Analytical Procedure for the Quantification of in vitro Induced Pt- and Pd-DNA Adducts in Human Lung Cells.

In: Zereini F, Alt F (eds.) Palladium Emissions in the Environment. Analytical Methods, Environmental Assessment and Health Effects. Springer Verlag (2005), pp. 325-341.


Burmeister B, Schwerdtle T, Poser I, Müller W-U, Rettenmeier AW, Hartwig A, Seemayer NH and Dopp E (2004)

Effects of asbestos on initiation of DNA damage, induction of DNA strand breaks, P53-expression and apoptosis in primary, SV40-transformed and malignant human mesothelial cells.

Mutat Res (2004), 558, 81 - 92.


Blessing H, Kraus S, Heindl P, Bal W and Hartwig A

Interaction of selenium compounds with zinc finger proteins involved in DNA repair.

Eur J Biochem (2004), 271, 3190 - 3199.


Kopera E, Schwerdtle T, Hartwig A, Bal W

Co(II) and Cd(II) substitute for Zn(II) in the zinc finger derived from the DNA repair protein XPA, demonstrating a variety of potential mechanisms of toxicity.

Chem Res Toxicol (2004), 17, 1452 - 1458.


Hartwig A, Blessing H, Schwerdtle T and Walter I

Zinkfingerstrukturen in DNA-Reparaturproteinen als potentielle Angriffspunkte für toxische Metallionen und essentielle Spurenelemente.

In: Schriftenreihe der Gesellschaft für Mineral­stoffe und Spurenelemente e.V., Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart (2004), pp 1 – 6.


Hartwig A, Blessing H, Schwerdtle T and Walter I (2003)

Modulation of DNA repair processes by arsenic and selenium compounds.

Toxicology (2003), 193, 161 – 169.


Schwerdtle T, Walter I and Hartwig A

Arsenite and its biomethylated metabolites interfere with the formation and repair of stable BPDE-induced DNA adducts in human cells and impair XPAzf and Fpg.

DNA Repair (2003), 2, 1449 - 1463.


Roul F, Gosse F, Delincée H, Hartwig A, Marchioni E, Miesch M, Werner D and Burnouf D

Food-borne radiolytic compounds promote experimental colon carcinogenesis.

Nutr Cancer (2003), 44, 189 - 191.


Schwerdtle T, Walter I, Mackiw I and Hartwig A

Induction of oxidative DNA damage by arsenite and its trivalent and pentavalent methylated metabolites in cultured human cells and isolated DNA.

Carcinogenesis (2003), 24, 967 – 974.


ESCODD

Measurement of DNA oxidation in human cells by chromatographic and enzymic methods.

Free Radical Biol Med (2003), 34, 1089 – 1099.


Bal W, Schwerdtle T and Hartwig A

Mechanisms of nickel assault on the zinc finger of DNA repair protein XPA.

Chem Res Toxicol (2003), 16, 242 - 248.


Hartwig A, Pelzer A, Asmuss M and Bürkle A

Very low concentrations of arsenite suppress poly(ADP-ribosyl)ation in mammalian cells.

Int J Cancer (2003), 104, 1 – 6.


Hartwig A, Schwerdtle T and Walter I

Current aspects on the genotoxicity of arsenite and its methylated metabolites: Oxidative stress and interactions with the cellular response to DNA damage.

In: Organic Metal and Metalloid Species in the EnvironmentHirner AV, Emons H (eds), Springer Verlag 2003, Berlin / Heidelberg (2003), pp 221-234.


Raul F, Gossé F, Delincée H, Hartwig A, Marchioni E, Miesch M, Werner D and Burnouf D

Food-borne radiolytic compounds (2-alkylcyclobutanones) may promote experimental colon carcinogenesis.

Nutr Cancer (2002), 44, 188–191.


ESCODD

Comparative analysis of baseline 8-oxoguanine in mammalian cell DNA, by different methods in different laboratories; an approach to consensus.

Carcinogenesis (2002), 23, 2129 – 2133.


Horvatovich P, Raul F, Miesch M, Burnouf D, Delincee H, Hartwig A, Werner D and Marchioni E

Detection of 2-alkylcyclobutanones, markers for irradiated foods, in adipose tissues of animals fed with these substances.

J Food Protect (2002), 65, 1610 – 1613.


Miesch, M, Horvatovich P, Burnouf D, Delincee H, Hartwig A, Raul F, Werner D and Marchioni E

Efficient reaction pathway for the synthesis of saturated and mono-unsaturated 2-alkylcyclobutanones.

Radiat Phys Chem (2002), 65, 233 - 239.


Hartwig A, Asmuss M, Ehleben I, Herzer U, Kostelac D, Pelzer A, Schwerdtle T and Bürkle A

Interference by toxic metal ions with DNA repair processes and cell cycle control: molecular mechanisms.

Environ Health Persp (2002), 110, 797 - 799.


ESCODD

Inter-laboratory validation of procedures for measuring 8-oxo-7,8-dihydroguanine/8-oxo-7,8-dihydro-2'-deoxyguanosine in DNA.

Free Radical Res (2002), 36, 239 – 245.


Jensen B.R. and ESCODD

Comparison of results from different laboratories in measuring 8-oxo-2'-deoxyguanosine in synthetic oligonucleotides.

Free Radical Res (2002), 36, 239 – 245.


Hartwig A, Asmuss M, Blessing H, Hoffmann S, Khandelwal S, Pelzer A and Bürkle A

Interference by toxic metal ions with zinc-dependent proteins involved in maintaining genomic stability.

Food Chem Toxicol (2002), 40, 1179 – 1184.


Hartwig A and Schwerdtle T

Interactions by carcinogenic metal compounds with DNA repair processes: toxicological implications.

Toxicol Lett (2002), 127, 47 – 54.


Schwerdtle T, Seidel A and Hartwig A

Effect of soluble and particulate nickel compounds on the formation and repair of stable benzo[a]pyrene DNA adducts in human lung cells.

Carcinogenesis (2002), 23, 47 – 53.


Hartwig A

Role of DNA repair in particle- and fiber-induced lung injury.

Inhal Toxicol (2002), 14, 91 - 100.


Greim H, Borm P, Schins R, Donaldson K, Driscoll K, Hartwig A, Kuempel E, Oberdörster G and Speit G

Toxicity of fibers and particles – Report of the workshop held in Munich, Germany, October 26 – 27, 2000.

Inhal Toxicol (2001), 13, 737 – 754.


Merzenich M, Hartwig A, Ahrens W, Beyersmann D, Scholze M, Timm J and Jöckel KH

Biomonitoring on carcinogenic metals and oxidative DNA damage in a cross-sectional study.

Cancer Epidem Biomarkers Prev (2001), 10, 515 – 522.


Hartwig A

Zinc finger proteins as potential targets for toxic metal ions: Differential effects on structure and function.

Antioxid Redox Signaling (2001), 3, 625 – 634.


Hartwig A, Kasper P, Madle S, Speit G, Staedtler F and Sengstag C

The potential use of mutation spectra in cancer releated genes in genetic toxicology: a statement of a GUM working group.

Mutat Res (2001), 473, 263 – 267.


Hartwig A

Role of magnesium in genomic stability.

Mutat Res (2001), 475, 113 - 121.


Asmuss M, Mullenders LHF, Eker A and Hartwig A

Differential effects of toxic metal compounds on the activities of Fpg and XPA, two zinc finger proteins involved in DNA repair.

Carcinogenesis (2000), 21, 2097 - 2104.


Hartwig A, Gröblinghoff UD, Hiemstra Y, Mullenders LHF

Inhibition of DNA repair processes by inorganic arsenic.

In: Eisenbrand G, Dayan AD, Elias PS, Grunow W and Schlatter J (eds) Carcinogenic and Anticarcinogenic Factors in Food, Wiley- VCH (2000), pp 478 - 481.